semante

Journal

On GLP-1, metabolic health, and the science of the body.

Featured · Muscle

Why GLP-1 users lose muscle — and what the research says about preventing it.

Up to 40% of weight lost on semaglutide can come from lean mass. This is not a minor side effect. Here is what the clinical literature shows about creatine as an intervention.

8 min read · Semante Journal

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Nutrition

The five nutrients most depleted by GLP-1 therapy — and how to address them.

Reduced food intake creates cumulative micronutrient gaps. B12, magnesium, potassium, iron, and vitamin D are where most people start to notice the difference.

6 min read

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Science

Berberine and GLP-1: the mechanism explained.

Berberine activates AMPK — the same cellular pathway that GLP-1 receptor agonists work alongside. Here is what the published research shows.

5 min read

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Lifestyle

Building a supplement routine around your GLP-1 injection schedule.

When to take Amplify, when to take Preserve, and how to build consistency into a routine that already involves a weekly injection.

4 min read

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