No. 01 · Amplify
No. 02 · Preserve
60 caps + powder · 30-day supply
The complete stack
Two problems. Two formulas. One system.
Amplify asks your GLP-1 medication to work harder. Preserve protects the muscle and minerals your medication would otherwise deplete. Together, they address the two primary physiological costs of GLP-1 therapy.
$74/month
Cancel or pause anytime. No commitment.
GMP certified · Third-party tested · USA made
How the system works
One amplifies. One protects.
No. 01
Amplify
The amplifier
Berberine activates AMPK — the enzyme that stimulates your gut to produce more GLP-1 naturally. Your medication mimics GLP-1. Amplify helps your body make more of it.
Berberine HCl 97% · Berberine HCl 8%
$49/month alone
Full ingredient list →No. 02
Preserve
The protector
Creatine monohydrate at the gold-standard 5g dose preserves lean muscle during caloric restriction. Electrolytes replace what reduced food intake no longer provides.
Creatine 5,000mg · Magnesium · Sodium · Potassium
$44/month alone
Full ingredient list →Bought separately: $93/month.
Together as Complete: $74/month.
You save $19 every month, $228 every year.
Built for
Anyone whose medication is working.
You've lost weight but feel weaker
Preserve addresses the muscle loss that accompanies GLP-1 weight reduction — the part the medication does not protect against.
Your energy has dropped since starting
Amplify supports the metabolic pathway GLP-1 medications activate — naturally, through AMPK stimulation rather than synthetic substitution.
You want your medication to do more
Berberine works alongside semaglutide and tirzepatide — not as a replacement but as a complement. Two mechanisms, one direction.
You're thinking long-term
Complete is designed for sustained use — the kind of daily support that compounds over months, not days. Both formulas reward consistency.
Full contents
Amplify
Berberine HCl 97%
Berberine HCl 8%
Cellulose capsule
Olive oil
60 capsules · 2 per day
Preserve
Creatine monohydrate 5,000mg
Magnesium malate 60mg
Sodium 1,000mg
Potassium chloride 200mg
Stevia
30 servings · 1 scoop per day
No proprietary blends. Full ingredient disclosure on both formulas. COA available on request.
Your daily ritual
Morning and any time.
Amplify — mornings
Two capsules with breakfast. Berberine absorbs better with food, and mornings are a natural anchor for the habit.
Preserve — any time
One scoop in 250ml water. Morning, midday, or evening — there is no wrong time for creatine. Consistency is the only variable that matters.
Our commitment
30 days. Full refund. No questions.
If Semante Complete is not right for you within the first 30 days, contact us for a complete refund. We ask only that you give both products a genuine try — metabolic changes take time, and the compounds in Complete reward consistency over speed.
Questions